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吸毒者中乙肝病毒/艾滋病毒/丙型肝炎病毒的危险因素:对一个病理依赖科就诊者的调查

Risk factors for HBV/HIV/HCV in drug addicts: a survey of attendees of a department of pathological dependence.

作者信息

Napoli C, Tafuri S, Pignataro N, Tedesco G, Maria A Santa, Quarto M

机构信息

Department of Biomedical Sciences, Hygiene Section, University of Bari Aldo Moro, Bari Hospital Trust, Bari, Italy.

出版信息

J Prev Med Hyg. 2010 Sep;51(3):101-4.

PMID:21361113
Abstract

INTRODUCTION

This study aims to determine risk factors for the acquisition of HIV, HBV and HCV infections among Injection Drug Users (IDUs) who attended the out-patient clinic of the Department of Pathological Dependence at Bari Hospital in Bari Province (Italy).

METHODS

The study was conducted in the year 2008 using the information available in the out-patient files of 291 drug addicts who were undergoing treatment.

RESULTS

Their average age was 29.3 and 133 (45.7%) of them were affected by HIV/HBV/WHCV. The use of injected heroin, being separated or divorced, and having committed a crime were found to be risk factors for infection by HIV/ HBV/ HCV, while having a school diploma or a university degree and the use of cannabinoids were negatively associated with the infective diseases.

DISCUSSION AND CONCLUSIONS

While the data from the Italian Departments of Pathological Dependence concerning HIV diffusion in treated patients have been showing a reduction in the number of cases of seropositivity, drug addiction in industrialized countries is still the second most important risk factor, after promiscuous sexual behaviour, for infection by parenteral transmission. Correct risk assessment is essential for the planning of effective strategies for primary and secondary prevention.

摘要

引言

本研究旨在确定在意大利巴里省巴里医院病理依赖科门诊就诊的注射吸毒者中感染艾滋病毒、乙肝病毒和丙肝病毒的风险因素。

方法

该研究于2008年开展,利用了291名正在接受治疗的吸毒者门诊档案中的现有信息。

结果

他们的平均年龄为29.3岁,其中133人(45.7%)感染了艾滋病毒/乙肝病毒/丙肝病毒。使用注射用海洛因、分居或离婚以及有犯罪记录被发现是感染艾滋病毒/乙肝病毒/丙肝病毒的风险因素,而拥有高中或大学学历以及使用大麻则与这些传染病呈负相关。

讨论与结论

虽然意大利病理依赖部门提供的有关接受治疗患者中艾滋病毒传播的数据显示血清阳性病例数量有所减少,但在工业化国家,药物成瘾仍然是仅次于滥交性行为的第二大重要经肠道外传播感染的风险因素。正确的风险评估对于制定有效的一级和二级预防策略至关重要。

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