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Good manufacturing practice-grade cytotoxic T lymphocytes specific for latent membrane proteins (LMP)-1 and LMP2 for patients with Epstein-Barr virus-associated lymphoma.

作者信息

Bollard Catherine M, Gottschalk Stephen, Helen Huls M, Leen Ann M, Gee Adrian P, Rooney Cliona M

机构信息

Center for Cell and Gene Therapy, Department of Pediatrics, Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital, Houston, Texas 77030, USA.

出版信息

Cytotherapy. 2011 May;13(5):518-22. doi: 10.3109/14653249.2011.561983. Epub 2011 Mar 1.

DOI:10.3109/14653249.2011.561983
PMID:21361747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3186062/
Abstract
摘要

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Good manufacturing practice-grade cytotoxic T lymphocytes specific for latent membrane proteins (LMP)-1 and LMP2 for patients with Epstein-Barr virus-associated lymphoma.用于爱泼斯坦-巴尔病毒相关淋巴瘤患者的、针对潜伏膜蛋白（LMP）-1和LMP2的药品生产质量管理规范级细胞毒性T淋巴细胞。
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本文引用的文献

1
Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex).使用透气快速扩增培养器（G-Rex）加速用于临床前和临床应用的抗原特异性 T 细胞的生产。
J Immunother. 2010 Apr;33(3):305-15. doi: 10.1097/CJI.0b013e3181c0c3cb.
2
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer.肿瘤抗原呈递细胞基因改造及T淋巴细胞转移后复发淋巴瘤的完全缓解
Blood. 2007 Oct 15;110(8):2838-45. doi: 10.1182/blood-2007-05-091280. Epub 2007 Jul 3.
3
Contact-activated monocytes: efficient antigen presenting cells for the stimulation of antigen-specific T cells.接触激活的单核细胞：用于刺激抗原特异性T细胞的高效抗原呈递细胞。
J Immunother. 2007 Jan;30(1):96-107. doi: 10.1097/01.cji.0000211325.30525.84.
4
Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease.针对爱泼斯坦-巴尔病毒阳性霍奇金淋巴瘤的细胞毒性T淋巴细胞疗法。
J Exp Med. 2004 Dec 20;200(12):1623-33. doi: 10.1084/jem.20040890.
5
The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease.用于从复发的EBV阳性霍奇金病患者进行过继性转移的LMP2特异性CTL的产生及特性分析
J Immunother. 2004 Jul-Aug;27(4):317-27. doi: 10.1097/00002371-200407000-00008.
6
Large-scale expansion of dendritic cell-primed polyclonal human cytotoxic T-lymphocyte lines using lymphoblastoid cell lines for adoptive immunotherapy.利用淋巴母细胞系大规模扩增树突状细胞致敏的多克隆人细胞毒性T淋巴细胞系用于过继性免疫治疗
J Immunother. 2003 May-Jun;26(3):241-56. doi: 10.1097/00002371-200305000-00008.
7
Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignancies.产生针对EB病毒次要LMP1抗原的细胞毒性T淋巴细胞用于EB病毒相关恶性肿瘤的过继性免疫治疗。
Blood. 2003 Mar 1;101(5):1905-12. doi: 10.1182/blood-2002-05-1514. Epub 2002 Oct 31.
8
Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the treatment of patients with EBV-positive relapsed Hodgkin's disease.用于治疗EBV阳性复发霍奇金淋巴瘤患者的爱泼斯坦-巴尔病毒（EBV）特异性细胞毒性T淋巴细胞。
Blood. 1998 Apr 15;91(8):2925-34.
9
Production of genetically modified Epstein-Barr virus-specific cytotoxic T cells for adoptive transfer to patients at high risk of EBV-associated lymphoproliferative disease.生产用于过继转移至患EB病毒相关淋巴增殖性疾病高风险患者的转基因爱泼斯坦-巴尔病毒特异性细胞毒性T细胞。
J Hematother. 1995 Apr;4(2):73-9. doi: 10.1089/scd.1.1995.4.73.
10
Release of infectious Epstein-Barr virus by transformed marmoset leukocytes.转化的狨猴白细胞释放传染性爱泼斯坦-巴尔病毒。
Proc Natl Acad Sci U S A. 1973 Jan;70(1):190-4. doi: 10.1073/pnas.70.1.190.