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在未经选择的急诊患者中,通过即时 HbA1C 检测诊断未确诊和控制不佳的糖尿病的患病率。

Prevalence of undiagnosed and suboptimally controlled diabetes by point-of-care HbA1C in unselected emergency department patients.

机构信息

Department of Emergency Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

出版信息

Acad Emerg Med. 2011 Mar;18(3):326-9. doi: 10.1111/j.1553-2712.2011.01014.x. Epub 2011 Mar 1.

DOI:10.1111/j.1553-2712.2011.01014.x
PMID:21362098
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3529908/
Abstract

OBJECTIVES

The objective was to estimate the glycemic control of patients with known diabetes and to assess the prevalence of undiagnosed diabetes in an unselected emergency department (ED) population. Secondary objectives include evaluating the prevalence of undiagnosed diabetes in high-risk groups of ED patients such as Hispanic patients, African Americans, and patients with body mass index (BMI) ≥ 30 kg/m(2) .

METHODS

A convenience sample of adult ED patients was screened for diabetes using a National Glycohemoglobin Standardization Program-certified point-of-care (POC) glycated hemoglobin (HbA1C) meter at a single academic medical center during eight 24-hour periods. Diabetes was defined as HbA1C ≥ 6.5%, consistent with new American Diabetes Association (ADA) guidelines.

RESULTS

Of the 1,611 patients evaluated in the ED during the study period, 313 were included in the study sample. Of these, 15% reported a history of diabetes, 42% of whom were suboptimally controlled. An additional 14% of the study sample was found to have previously undiagnosed diabetes. In our limited sample, the prevalence of previously undiagnosed diabetes in Hispanics, African Americans, and patients with BMI ≥ 30 kg/m(2) was 14, 27, and 22%, respectively.

CONCLUSIONS

Patients in our sample had a high prevalence of suboptimally controlled and undiagnosed diabetes. New POC HbA1C devices and simplified diagnostic criteria for diabetes significantly enhance the possibility of ED-based screening programs. Future research should validate our findings in a broader array of EDs and study the acceptance of such ED-based diabetes screening programs.

摘要

目的

评估已知糖尿病患者的血糖控制情况,并评估未确诊糖尿病在未经选择的急诊科(ED)人群中的患病率。次要目标包括评估 ED 患者中高危人群(如西班牙裔患者、非裔美国人和 BMI≥30kg/m²的患者)中未确诊糖尿病的患病率。

方法

在一个学术医疗中心的 8 个 24 小时时段内,使用经国家糖化血红蛋白标准化计划认证的即时检测(POC)糖化血红蛋白(HbA1C)仪,对急诊科的成年 ED 患者进行了糖尿病筛查。糖尿病的定义为 HbA1C≥6.5%,符合新的美国糖尿病协会(ADA)指南。

结果

在研究期间,在 ED 中评估的 1611 例患者中,有 313 例纳入了研究样本。其中,15%的患者报告有糖尿病病史,其中 42%的患者血糖控制不理想。研究样本中还有 14%的患者被发现患有以前未被诊断的糖尿病。在我们的有限样本中,西班牙裔、非裔美国人和 BMI≥30kg/m²的患者中以前未被诊断的糖尿病的患病率分别为 14%、27%和 22%。

结论

我们样本中的患者存在血糖控制不理想和未确诊糖尿病的高患病率。新型 POC HbA1C 检测设备和简化的糖尿病诊断标准显著提高了 ED 基于筛查的可能性。未来的研究应在更广泛的 ED 中验证我们的发现,并研究对基于 ED 的糖尿病筛查计划的接受程度。

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