Albendazole: a more effective antigiardial agent in vitro than metronidazole or tinidazole.
作者信息
Meloni B P, Thompson R C, Reynoldson J A, Seville P
机构信息
Division of Veterinary Biology, School of Veterinary Studies, Murdoch University, Western Australia.
出版信息
Trans R Soc Trop Med Hyg. 1990 May-Jun;84(3):375-9. doi: 10.1016/0035-9203(90)90324-8.
PMID:2136253
Abstract
The effects of albendazole were assessed against Giardia duodenalis in vitro and compared with those of tinidazole and metronidazole. Trophozoite morphology, adherence and viability were markedly affected by albendazole, to a far greater extent than by either metronidazole or tinidazole. The results of this study, and in particular the superior potency of albendazole in vitro, are discussed with respect to its potential value as a new approach to the chemotherapy of giardiasis.
摘要
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