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微需氧寄生虫中的耐药性

Drug Resistance in the Microaerophilic Parasite .

作者信息

Leitsch David

机构信息

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

出版信息

Curr Trop Med Rep. 2015;2(3):128-135. doi: 10.1007/s40475-015-0051-1.

Abstract

The microaerophilic parasite is a causative agent of dysentery affecting hundreds of millions of people around the globe every year. The symptoms of the disease, commonly referred to as giardiasis, are diarrhea, nausea, and malabsorption. Treatment of giardiasis is exclusively based on chemotherapy with antigiardial drugs, including metronidazole, albendazole, and nitazoxanide. In this review, all drugs currently used in the treatment of infections are discussed with a special emphasis on treatment failure and drug resistance.

摘要

这种微需氧寄生虫是痢疾的病原体,每年影响全球数亿人。这种疾病的症状通常称为贾第虫病,包括腹泻、恶心和吸收不良。贾第虫病的治疗完全基于使用抗贾第虫药物进行化疗,这些药物包括甲硝唑、阿苯达唑和硝唑尼特。在这篇综述中,讨论了目前用于治疗感染的所有药物,特别强调了治疗失败和耐药性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7938/4523694/984bf49cf299/40475_2015_51_Fig1_HTML.jpg

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