肿瘤坏死因子-α与创伤弧菌感染患者的死亡率
Tumor necrosis factor-α and mortality in patients infected with Vibrio vulnificus.
作者信息
Lee Jun-Young, Kim Dong-Min, Yun Na Ra, Neupane Ganesh Prasad, Jung Sook-In, Park Kyung-Hwa, Jang Hee Chang, Lee Chang Seop, Lee Sun Hee
机构信息
Department of Orthopaedic Surgery, School of Medicine, Chosun University, Gwangju, Republic of Korea.
出版信息
Am J Trop Med Hyg. 2011 Mar;84(3):426-8. doi: 10.4269/ajtmh.2011.10-0310.
Abstract
Serum tumor necrosis factor-α (TNF-α) was evaluated in Vibrio vulnificus-infected patients at admission. The median TNF-α concentration in the non-survivor group was determined to be 261.0 pg/mL, in contrast to 69.5 pg/mL in the survivor group (P = 0.001). Hence, serum TNF-α concentration may potentially be an early predictor of the mortality in patients with Vibrio septicemia.
摘要
在创伤弧菌感染患者入院时评估血清肿瘤坏死因子-α（TNF-α）。非存活组的TNF-α浓度中位数确定为261.0 pg/mL，而存活组为69.5 pg/mL（P = 0.001）。因此，血清TNF-α浓度可能是创伤弧菌败血症患者死亡率的早期预测指标。
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