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Pharmacotherapy: hypothyroidism-should levothyroxine be taken at bedtime?

作者信息

Vanderpump Mark

出版信息

Nat Rev Endocrinol. 2011 Apr;7(4):195-6. doi: 10.1038/nrendo.2011.29. Epub 2011 Mar 1.

DOI:10.1038/nrendo.2011.29
PMID:21364516
Abstract
摘要

相似文献

1
Pharmacotherapy: hypothyroidism-should levothyroxine be taken at bedtime?药物治疗:甲状腺功能减退症——左甲状腺素应该在睡前服用吗?
Nat Rev Endocrinol. 2011 Apr;7(4):195-6. doi: 10.1038/nrendo.2011.29. Epub 2011 Mar 1.
2
Levothyroxine in psychiatry: issues related to absorption after oral dosing.左甲状腺素在精神病学中的应用:与口服给药后吸收相关的问题。
J Clin Psychiatry. 2013 Aug;74(8):e744-6. doi: 10.4088/JCP.13f08668.
3
Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial.晚上服用左甲状腺素与早上服用左甲状腺素的效果比较:一项随机双盲交叉试验。
Arch Intern Med. 2010 Dec 13;170(22):1996-2003. doi: 10.1001/archinternmed.2010.436.
4
Thyroxine replacement therapy--too much of a good thing?甲状腺素替代疗法——好事过头了?
Lancet. 1990 Dec 1;336(8727):1352-3.
5
Incidentally elevated thyrotropin in otherwise properly treated hypothyroid patients does not require higher levothyroxine dose.
Acta Clin Croat. 2014 Sep;53(3):291-3.
6
Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients.甲状腺功能减退患者晚间与晨间服用甲状腺素对血清甲状腺激素谱的影响。
Clin Endocrinol (Oxf). 2007 Jan;66(1):43-8. doi: 10.1111/j.1365-2265.2006.02681.x.
7
Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism.甲状腺功能减退症女性孕期左甲状腺素需求量增加的时间和幅度。
N Engl J Med. 2004 Jul 15;351(3):241-9. doi: 10.1056/NEJMoa040079.
8
Serum thyrotropin in primary hypothyroidism. A possible predictor of optimal daily levothyroxine dose in primary hypothyroidism.原发性甲状腺功能减退症中的血清促甲状腺激素。原发性甲状腺功能减退症中每日左甲状腺素最佳剂量的一个可能预测指标。
Arch Intern Med. 1995 May 22;155(10):1046-8.
9
Estimation of a physiologic replacement dose of levothyroxine in elderly patients with hypothyroidism.老年甲状腺功能减退患者左甲状腺素生理替代剂量的估算。
Arch Intern Med. 1984 Sep;144(9):1752-4.
10
Timing of levothyroxine administration affects serum thyrotropin concentration.左甲状腺素给药时间会影响血清促甲状腺激素浓度。
J Clin Endocrinol Metab. 2009 Oct;94(10):3905-12. doi: 10.1210/jc.2009-0860. Epub 2009 Jul 7.

引用本文的文献

1
Individualised requirements for optimum treatment of hypothyroidism: complex needs, limited options.甲状腺功能减退症最佳治疗的个体化需求:需求复杂,选择有限。
Drugs Context. 2019 Aug 13;8:212597. doi: 10.7573/dic.212597. eCollection 2019.

本文引用的文献

1
Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial.晚上服用左甲状腺素与早上服用左甲状腺素的效果比较:一项随机双盲交叉试验。
Arch Intern Med. 2010 Dec 13;170(22):1996-2003. doi: 10.1001/archinternmed.2010.436.
2
Adequacy of thyroid hormone replacement in a general population.一般人群中甲状腺激素替代的充足性。
QJM. 2011 May;104(5):395-401. doi: 10.1093/qjmed/hcq222. Epub 2010 Nov 24.
3
Timing of levothyroxine administration affects serum thyrotropin concentration.左甲状腺素给药时间会影响血清促甲状腺激素浓度。
J Clin Endocrinol Metab. 2009 Oct;94(10):3905-12. doi: 10.1210/jc.2009-0860. Epub 2009 Jul 7.
4
High frequency of and factors associated with thyroid hormone over-replacement and under-replacement in men and women aged 65 and over.65岁及以上男性和女性甲状腺激素替代过量与不足的高发生率及相关因素
J Clin Endocrinol Metab. 2009 Apr;94(4):1342-5. doi: 10.1210/jc.2008-1696. Epub 2009 Jan 6.
5
Management of hypothyroidism in adults.成人甲状腺功能减退症的管理
BMJ. 2008 Jul 28;337:a801. doi: 10.1136/bmj.a801.
6
Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients.甲状腺功能减退患者晚间与晨间服用甲状腺素对血清甲状腺激素谱的影响。
Clin Endocrinol (Oxf). 2007 Jan;66(1):43-8. doi: 10.1111/j.1365-2265.2006.02681.x.
7
Psychological well-being correlates with free thyroxine but not free 3,5,3'-triiodothyronine levels in patients on thyroid hormone replacement.在接受甲状腺激素替代治疗的患者中,心理健康与游离甲状腺素相关,而与游离三碘甲状腺原氨酸水平无关。
J Clin Endocrinol Metab. 2006 Sep;91(9):3389-93. doi: 10.1210/jc.2006-0414. Epub 2006 Jun 27.
8
Small changes in thyroxine dosage do not produce measurable changes in hypothyroid symptoms, well-being, or quality of life: results of a double-blind, randomized clinical trial.甲状腺素剂量的微小变化不会在甲状腺功能减退症状、健康状况或生活质量方面产生可测量的变化:一项双盲随机临床试验的结果
J Clin Endocrinol Metab. 2006 Jul;91(7):2624-30. doi: 10.1210/jc.2006-0099. Epub 2006 May 2.
9
Thyroxine prescription in the community: serum thyroid stimulating hormone level assays as an indicator of undertreatment or overtreatment.社区中的甲状腺素处方:血清促甲状腺激素水平测定作为治疗不足或治疗过度的指标
Br J Gen Pract. 1993 Mar;43(368):107-9.
10
Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans.左甲状腺素在甲状腺功能减退治疗中的替代剂量、代谢及生物利用度。三碘甲状腺原氨酸在人体垂体反馈中的作用。
N Engl J Med. 1987 Mar 26;316(13):764-70. doi: 10.1056/NEJM198703263161302.