Mudunuri Suresh B, Kumar Pankaj, Rao Allam Appa, Pallamsetty S, Nagarajaram H A
Bioinformation. 2010 Nov 1;5(5):221-3. doi: 10.6026/97320630005221.
Microsatellites are ubiquitous short tandem repeats found in all known genomes and are known to play a very important role in various studies and fields including DNA fingerprinting, paternity studies, evolutionary studies, virulence and adaptation of certain bacteria and viruses etc. Due to the sequencing of several genomes and the availability of enormous amounts of sequence data during the past few years, computational studies of microsatellites are of interest for many researchers. In this context, we developed a software tool called Imperfect Microsatellite Extractor (IMEx), to extract perfect, imperfect and compound microsatellites from genome sequences along with their complete statistics. Recently we developed a user-friendly graphical-interface using JAVA for IMEx to be used as a stand-alone software named G-IMEx. G-IMEx takes a nucleotide sequence as an input and the results are produced in both html and text formats. The Linux version of G-IMEx can be downloaded for free from http://www.cdfd.org.in/imex.
微卫星是在所有已知基因组中普遍存在的短串联重复序列，已知在包括DNA指纹识别、亲子鉴定研究、进化研究、某些细菌和病毒的毒力及适应性等各种研究和领域中发挥着非常重要的作用。由于过去几年多个基因组的测序以及大量序列数据的可得性，微卫星的计算研究引起了许多研究人员的兴趣。在此背景下，我们开发了一个名为不完美微卫星提取器（IMEx）的软件工具，用于从基因组序列中提取完美、不完美和复合微卫星及其完整统计信息。最近，我们使用JAVA为IMEx开发了一个用户友好的图形界面，将其用作名为G-IMEx的独立软件。G-IMEx以核苷酸序列作为输入，并以html和文本格式生成结果。G-IMEx的Linux版本可从http://www.cdfd.org.in/imex免费下载。
