Frenkel Felix E, Korotkova Maria A, Korotkov Eugene V
Institute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Ave. 33, bld. 2, 119071 Moscow, Russia.
National Research Nuclear University "MEPhI", Kashirskoe Shosse 31, Moscow 115409, Russia.
Biomed Res Int. 2017;2017:7949287. doi: 10.1155/2017/7949287. Epub 2017 Jan 15.
. We analyzed several prokaryotic and eukaryotic genomes looking for the periodicity sequences availability and employing a new mathematical method. The method envisaged using the random position weight matrices and dynamic programming. Insertions and deletions were allowed inside periodicities, thus adding a novelty to the results we obtained. A periodicity length, one of the key periodicity features, varied from 2 to 50 nt. Totally over 60,000 periodicity sequences were found in 15 genomes including some chromosomes of the (partial), , and genomes.
我们分析了多个原核生物和真核生物基因组，寻找周期性序列的可用性，并采用了一种新的数学方法。该方法设想使用随机位置权重矩阵和动态规划。周期性内部允许插入和缺失，从而为我们获得的结果增添了新颖性。周期性长度是关键的周期性特征之一，范围从2到50个核苷酸。在包括（部分）、、和基因组的一些染色体在内的15个基因组中总共发现了超过60,000个周期性序列。
