Lutz W, Sułkowski W
Department of Laboratory Diagnostics, Nofer Institute of Occupational Medicine, Lodz, Poland.
Pol J Occup Med. 1990;3(3):257-72.
The authors present a review of literature showing that the variations in xenobiotic oxidation phenotype, in the presence of cytochromes P-450, may be responsible, to a certain extent, for the varied individual susceptibility to neoplasm induced by chemical carcinogens. The evidence collected revealed that in the human population, one may distinguish individuals with high cytochrome activity and those in whom this reaction is low or even absent.
作者发表了一篇文献综述，表明在细胞色素P - 450存在的情况下，异生物质氧化表型的变化在一定程度上可能是个体对化学致癌物诱发肿瘤易感性不同的原因。收集到的证据显示，在人群中，可以区分出细胞色素活性高的个体和该反应低甚至缺乏的个体。
