Lebkowski W J
Kliniki Neurochirurgii AMB.
Rocz Akad Med Bialymst (1989). 1990;35-36:65-9.
Already Cushing pointed out that intracranial volume, thus the intracranial pressure, or ICP should exhibit an equilibrium state. Brain receives about 15% of the heart stroke volume. Cerebral blood flow (CBF) which is under control of an autoregulatory system, results from the cerebral perfusion pressure, or CPP being the difference between the mean arterial pressure and ICP. Intracranial pathology results in a reduced CBF, that under extreme conditions can lead to death. The up-to-date experiments indicate that both the ICP and arterial pressure can be successfully monitored for a quite long period. These observations make the choice of optimum therapy easier. According to some researchers such a monitoring has been introduced as a regular method of the neurosurgical intensive care.
库欣早已指出,颅内容积,进而颅内压(ICP)应呈现一种平衡状态。大脑接收约15%的心搏出量。脑血流量(CBF)受自身调节系统控制,它由脑灌注压(CPP)产生,CPP为平均动脉压与ICP之差。颅内病变会导致CBF降低,在极端情况下可导致死亡。最新实验表明,ICP和动脉压都能在相当长的一段时间内成功监测。这些观察结果使最佳治疗方案的选择更加容易。一些研究人员认为,这种监测已成为神经外科重症监护的常规方法。