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一例2009年甲型H1N1流感宫内传播疑似病例

[A suspected case of in utero transmission of influenza A (H1N1) 2009].

作者信息

Picone O, Bernabe-Dupont C, Vauloup-Fellous C, Castel C, Cordier A-G, Guillet M, Grangeot-Keros L, Boileau P, Benachi A, Frydman R

机构信息

INSERM U782, université Paris-Sud, Clamart, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2011 Sep;40(5):473-5. doi: 10.1016/j.jgyn.2011.01.014. Epub 2011 Mar 1.

DOI:10.1016/j.jgyn.2011.01.014
PMID:21367537
Abstract

A 34-year-old woman consulted the day before a scheduled caesarean for dry cough. A positive rhinopharyngeal sample for PCR testing for influenza A H1N1 led to a curative oseltamivir (Tamiflu®) treatment. At delivery a direct contact between the newborn and mother lasted only few seconds. The first healthy baby boy developped dry cough with a rhinopharyngeal sample positive for A H1N1. The minimal contact between mother and child and the positive neonatal sample only four hours after birth allow to think that it is a rare case of prenatal transmission of influenza A H1N1 to the fetus.

摘要

一名34岁女性在计划剖宫产的前一天因干咳前来咨询。鼻咽喉拭子进行甲型H1N1流感病毒PCR检测呈阳性,遂接受了可治愈的奥司他韦(达菲®)治疗。分娩时,新生儿与母亲的直接接触仅持续了几秒钟。第一个健康男婴出现干咳,鼻咽喉拭子检测甲型H1N1流感病毒呈阳性。母婴之间接触极少,且新生儿出生仅4小时后样本就呈阳性,这让人认为这是一例罕见的甲型H1N1流感病毒产前传播给胎儿的病例。

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