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Preparation of collagen-glycosaminoglycan copolymers for tissue regeneration.

作者信息

Chamberlain L J, Yannas I V

机构信息

Fibers and Polymers Laboratory, Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA.

出版信息

Methods Mol Med. 1999;18:3-17. doi: 10.1385/0-89603-516-6:3.

Abstract

Certain analogs of the extracellular matrix (ECM) have been shown to possess surprising morphogenetic activity during healing of lesions in various anatomical sites. This chapter describes methods for synthesis of the two ECM analogs that have been studied most extensively. The reader is referred to descriptions of these methods in the original literature (1-3). The biological activity of ECM analogs has been reviewed elsewhere (4).

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