人淋巴母细胞系中甲基磺酸丁酯的毒性和诱变性比较。
Comparison of toxicity and mutagenicity of butyl methanesulfonate among human lymphoblast lines.
作者信息
Slapikoff S A, Andon B M, Thilly W G
出版信息
Mutat Res. 1978 Oct;54(2):193-6. doi: 10.1016/0165-1161(78)90040-7.
PMID:213710
Abstract
The toxic and mutagenic effects of butyl methanesulfonate (BMS) were compared among four diploid human lymphoblast lines, MIT-2, WI-L2, MGL8B-2 and GM 130. The toxic and mutagenic effects of 24-h exposure to BMS were similar for the MIT-2, WI-L2 and MGL8B-2 lines, while the GM 130 line was strikingly resistant to the toxic and mutagenic effects of BMS.
摘要
在四种二倍体人类淋巴母细胞系MIT-2、WI-L2、MGL8B-2和GM 130中比较了甲磺酸丁酯（BMS）的毒性和诱变作用。MIT-2、WI-L2和MGL8B-2细胞系暴露于BMS 24小时后的毒性和诱变作用相似，而GM 130细胞系对BMS的毒性和诱变作用具有显著抗性。
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