Adolfo Lutz Institute -Regional Laboratory from São José do Rio Preto, São Paulo, SP, Brazil.
Trop Med Int Health. 2011 Jan;16(1):67-73. doi: 10.1111/j.1365-3156.2010.02681.x.
To evaluate retrospectively the microbiological profile of Mycobacterium species isolated from HIV-infected patients attending the HIV/TB reference health care units in São José do Rio Preto, Brazil.
Retrospective evaluation of all HIV-1 positive patients whose IAL-SJRP laboratorial analysis was positive for Mycobacterium sp. after diagnosis of HIV Infection, from January 2000 to December 2006.
Of 198 patients, acid-fast staining detected mycobacteria early in 41%. Culture revealed 52.5% to be infected with Mycobacterium tuberculosis (MT). 42.4% had non-tuberculous mycobacteria (NTM) and 5.1% had MT/NTM positive cultures. Eleven per cent of MT strains were resistant to at least one of the antimycobacterial drugs and 3.1% were multidrug resistant. 39.4% of isolated mycobacteria were NTM species.
Our data may serve as a starting point for further comparisons with other Brazilian regions and other developing countries. The data may provide important clues to the future understanding, prevention and control of such co-infections around the world.
回顾性评估巴西圣若泽-里波雷托 HIV/TB 参考医疗单位收治的 HIV 感染患者中分离出的分枝杆菌属的微生物特征。
对 2000 年 1 月至 2006 年 12 月间，经 IAL-SJRP 实验室分析诊断为 HIV 感染后其 IAL-SJRP 实验室分析呈分枝杆菌阳性的所有 HIV-1 阳性患者进行回顾性评估。
在 198 例患者中，41%的患者早期经酸染色法检测到分枝杆菌。培养结果显示 52.5%的患者感染结核分枝杆菌（MT）。42.4%的患者为非结核分枝杆菌（NTM），5.1%的患者 MT/NTM 培养阳性。11%的 MT 株对至少一种抗分枝杆菌药物具有耐药性，3.1%的 MT 株为耐多药。39.4%分离出的分枝杆菌为 NTM 种。
我们的数据可以作为与巴西其他地区和其他发展中国家进一步比较的起点。这些数据可能为未来全球范围内对这类合并感染的理解、预防和控制提供重要线索。
