Wilson S N, Surman O S, Colvin R, Ozonoff D, Gelenberg A J, Jenike M A, Manschreck T, Pato C
Department of Psychiatry, Massachusetts General Hospital, Boston.
J Clin Psychiatry. 1990 Feb;51(2):51-2.
Depression has been previously associated with immunologic dysfunction. The lymphocyte subsets of 10 patients with major depression were found to show a mean T4-T8 (helper-suppressor) ratio lower than that of controls, a difference attributable to increased numbers of suppressor cells in the depressed group. One possible cause of increased suppressor cells is prior or current viral infection.
抑郁症先前一直被认为与免疫功能紊乱有关。研究发现，10名重度抑郁症患者的淋巴细胞亚群显示，其平均T4-T8（辅助性T细胞-抑制性T细胞）比值低于对照组，这一差异归因于抑郁症组中抑制性细胞数量的增加。抑制性细胞增多的一个可能原因是既往或当前的病毒感染。
