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常规伤口处理与封闭式负压引流在感染性剖腹伤口中的应用比较——一项对照研究。

Conventional wound management versus a closed suction irrigation method for infected laparotomy wound--a comparative study.

机构信息

Department of Hepatobiliary Surgery, The First People's Hospital of Foshan, Foshan 528000, Guang Dong, China.

出版信息

Int J Surg. 2011;9(5):378-81. doi: 10.1016/j.ijsu.2011.02.012. Epub 2011 Mar 1.

Abstract

OBJECTIVE

The aim of this study was to evaluate the efficacy of a closed suction irrigation method for the management of infected laparotomy wounds.

METHODS

This is a retrospective study on consecutive patients with infected laparotomy wounds managed in a single tertiary referral hospital from January 2004 to March 2009. The wounds were laid open, debrided and cleansed with hydrogen peroxide, povidone iodine and normal saline. The wounds were either conventionally treated with normal saline dressings followed by secondary suturing when healthy granulation tissues were formed (the Control group) or by the closed suction irrigation method after suturing the wound (the Study Group).

RESULTS

There were 70 patients in the Study Group and 60 patients in the Control Group. The hospital stay (mean ± SD, 9.2 ± 0.1 vs. 20.5 ± 0.6 days, P < 0.001) and time to wound healing (mean ± SD, 8.1 ± 0.1 vs. 18.5 ± 0.6 days, P < 0.001) were significantly better in the Study Group than in the Control Group. The re-infection rate was also significantly lower in the Study Group (7.1% vs. 21.7%, P < 0.05).

CONCLUSIONS

Encouraging results were obtained with the use of the closed suction irrigation method for infected laparotomy wounds. The closed suction irrigation method decreased hospital stay and allowed early rehabilitation. The findings of our study need to be substantiated in large-scale randomized controlled trials.

摘要

目的

本研究旨在评估封闭式负压冲洗法在治疗感染性剖腹伤口中的疗效。

方法

这是一项回顾性研究,纳入了 2004 年 1 月至 2009 年 3 月期间在一家三级转诊医院接受治疗的连续感染性剖腹伤口患者。将伤口敞开,用双氧水、聚维酮碘和生理盐水清创。这些伤口要么采用常规生理盐水敷料治疗,待健康肉芽组织形成后再行二期缝合(对照组),要么在缝合伤口后采用封闭式负压冲洗法(研究组)。

结果

研究组有 70 例患者,对照组有 60 例患者。研究组的住院时间(均值±标准差,9.2±0.1 天 vs. 20.5±0.6 天,P<0.001)和伤口愈合时间(均值±标准差,8.1±0.1 天 vs. 18.5±0.6 天,P<0.001)明显短于对照组。研究组的再感染率也明显较低(7.1% vs. 21.7%,P<0.05)。

结论

封闭式负压冲洗法治疗感染性剖腹伤口效果良好。该方法缩短了住院时间,促进了早期康复。本研究的结果需要在大规模随机对照试验中得到证实。

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