Matsumoto Hideyuki, Shimizu Takahiro, Okabe Shingo, Konoma Yuko, Takahashi Toshiyuki, Hirakawa-Yamada Minako, Igeta Yukifusa, Hashida Hideji
Department of Neurology, Japanese Red Cross Medical Center, Japan.
Intern Med. 2011;50(5):509-13. doi: 10.2169/internalmedicine.50.4430. Epub 2011 Mar 1.
This report describes the case of a 71-year-old woman with a limited form of neuromyelitis optica (NMO) who had a longitudinally extensive spinal cord lesion from the fourth to the tenth thoracic vertebrae. Up to age 75, she had four subsequent recurrences of the myelitis within the same spinal cord area but with no optic neuritis. Anti-AQP4 antibody was seropositive. Recurrence within the same spinal cord area might be a characteristic clinical finding in NMO spectrum disorders. For such patients, examination for anti-AQP4 antibody might be necessary for the diagnosis and therapy of this disorder.
本报告描述了一名71岁患有局限性视神经脊髓炎（NMO）的女性病例，其脊髓病变纵向累及第四至第十胸椎。直至75岁，她在同一脊髓区域先后出现了4次脊髓炎复发，但未出现视神经炎。抗水通道蛋白4（AQP4）抗体血清学检测呈阳性。同一脊髓区域的复发可能是视神经脊髓炎谱系障碍的一个特征性临床发现。对于此类患者，检测抗AQP4抗体可能对该疾病的诊断和治疗很有必要。
