Kings College London School of Medicine, First Floor, Hodgkin Building, Guy's Campus, London, SE1 1UL, UK.
Int Urol Nephrol. 2012 Oct;44(5):1577-80. doi: 10.1007/s11255-011-9924-y. Epub 2011 Mar 4.
Conn's syndrome following renal transplantation is extremely rare. Here, we present two cases of persistent hypertension and hypokalemia, emerging after kidney transplantation, which proved resistant to medical treatment. In both patients, biochemical investigations elicited massively elevated plasma aldosterone levels and suppressed renin activity. Abdominal MRI demonstrated a 90- and 20-mm right adrenal tumour in cases 1 and 2, respectively. For both patients, curative treatment was achieved via laparoscopic right adrenalectomy.
Conn 综合征在肾移植后极为罕见。本文报道了 2 例肾移植后出现持续性高血压和低钾血症的病例，这些病例经药物治疗后仍无法缓解。在这 2 例患者中，生化检查均显示血浆醛固酮水平显著升高，肾素活性受到抑制。腹部 MRI 显示 1 号和 2 号患者右侧肾上腺肿瘤分别为 90mm 和 20mm。对这 2 例患者均采用腹腔镜右肾上腺切除术进行根治性治疗。
