Hogan D J
Division of Dermatology, University of Saskatchewan, University Hospital, Saskatoon, Canada.
Dermatol Clin. 1990 Jan;8(1):133-6.
Ethylenediamine would be an infrequent sensitizer if it were not present in a widely prescribed topical corticosteroid preparation that is applied to inflamed skin. Occupational allergic contact dermatitis to ethylenediamine is not common. The educational efforts of American dermatologists such as Dr. Alex Fisher have helped lead to the deletion of ethylenediamine from Mycolog cream. It is unfortunate that the same pharmaceutical company continues to use ethylenediamine in its products in other countries, as the continued popularity of these creams may allow ethylenediamine to remain a common sensitizer in some areas, particularly where inflammatory skin conditions are treated predominantly by nondermatologists.
如果乙二胺不存在于一种广泛处方的外用皮质类固醇制剂中,该制剂用于发炎的皮肤,那么它将是一种不常见的致敏原。职业性对乙二胺的过敏性接触性皮炎并不常见。像亚历克斯·费舍尔博士这样的美国皮肤科医生所做的教育工作,有助于导致乙二胺从Mycolog乳膏中被去除。不幸的是,同一家制药公司在其他国家的产品中继续使用乙二胺,因为这些乳膏的持续流行可能会使乙二胺在某些地区仍然是一种常见的致敏原,特别是在炎症性皮肤病主要由非皮肤科医生治疗的地方。