Baĭnova A, Khristeva V, Madzhunov I, Daneva Zh
Probl Khig. 1987;12:109-14.
During an examination of 47 workers engaged in ethylenediamine production subjective complaints of the skin were registered in 39% of them. Professional contact allergic dermatitis (26%) prevail over the contact irritative (6.5%) and lead very often to a change of employment for the operators. The epicutanic test with ethylenediamine and diethylene-triamine gives respectively 32 and 20% positiveness with high relative part of latent allergy. At compensated pH of the skin the sample for alkalic neutralization is prolonged in 42.9% of the workers. The ethylenediamine dermal absorption at concentrations in the air of the working area about MAC, is shown with methemoglobinemia registered in 15 operators. The raised methemoglobin in blood could be used with success as indirect test for exposure in hygiene-toxicological studies of workers exposed to ethylenediamine and aliphatic amines.
在对47名从事乙二胺生产的工人进行检查时，39%的工人有皮肤方面的主观不适主诉。职业性接触过敏性皮炎（26%）比接触刺激性皮炎（6.5%）更为常见，并且经常导致操作人员更换工作。用乙二胺和二乙烯三胺进行的皮肤试验分别有32%和20%呈阳性，其中潜在过敏的比例较高。在皮肤pH值代偿的情况下，42.9%的工人碱中和样本时间延长。在工作区域空气中浓度约为职业接触限值（MAC）时，15名操作人员出现高铁血红蛋白血症，表明有乙二胺经皮肤吸收。血液中高铁血红蛋白升高可成功地用作乙二胺和脂肪胺接触工人卫生毒理学研究中接触情况的间接检测指标。
