Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen - Nuremberg Medical School, Germany.
Head Neck. 2012 Jan;34(1):73-7. doi: 10.1002/hed.21687. Epub 2011 Mar 3.
The purpose of this study was to evaluate retrospectively the oncologic results of endoscopic and open surgical techniques in treating T2 glottic carcinomas.
The medical chart of 354 patients with T2 glottic cancer managed with primary surgery were reviewed. Laser microsurgery and frontolateral partial laryngectomy were compared for disease-specific survival and local control rates, incidence of major complications, and related tracheostomies. Additionally, the influence of the anterior commissure invasion on these oncologic parameters was evaluated.
No statistically significant differences were found between the surgical procedures regarding our oncologic parameters. A lower incidence of tracheotomies and complications were comparatively found for laser surgery. Tumor invasion of the anterior commissure did not seem to influence the oncologic results.
Transoral surgery seems to be the treatment of choice for T2 glottic cancer. In our view, open partial laryngectomy should be reserved for those cases in which the lesion cannot be adequately exposed by direct microlaryngoscopy.
本研究旨在回顾性评估内镜和开放式手术技术治疗 T2 声门型喉癌的肿瘤学结果。
回顾性分析了 354 例接受原发性手术治疗的 T2 声门型喉癌患者的病历。比较了激光显微手术和前外侧部分喉切除术在疾病特异性生存率和局部控制率、主要并发症发生率以及相关气管切开术方面的差异。此外，还评估了前连合侵犯对这些肿瘤学参数的影响。
在我们的肿瘤学参数方面，两种手术方法之间没有统计学上的显著差异。激光手术的气管切开术和并发症发生率较低。前连合侵犯似乎并不影响肿瘤学结果。
经口手术似乎是 T2 声门型喉癌的首选治疗方法。在我们看来，对于那些无法通过直接显微镜检查充分暴露的病变，应保留开放性部分喉切除术。
