Prazák J, Lásziková E, Ryska O, Ryska M
Klinika Anesteziologie, Resuscitace a Intenzivni péce 2. LF UK.
Rozhl Chir. 2010 Oct;89(10):642-6.
Acute liver failure is a severe condition with a very unfavourable prognosis. One of the common complications and limiting factors for the outcome is the development of the intracranial hypertension. The etiology and the pathogenetic pathways leading to the development of this fatal complication of acute liver failure is still not completely understood. The aim of this review is to inform about the actual knowledge of pathogenesis of the intracranial hypertension in acute liver failure. Finally, a new method of tissue metabolism monitoring--microdialysis--is shortly discussed as a perspective method in monitoring and research on acute liver failure.
急性肝衰竭是一种病情严重、预后极差的病症。颅内高压的发生是常见并发症之一，也是影响预后的限制因素。导致急性肝衰竭这一致命并发症的病因及发病机制尚未完全明确。本综述旨在介绍急性肝衰竭颅内高压发病机制的现有知识。最后，简要讨论了一种组织代谢监测的新方法——微透析，作为急性肝衰竭监测与研究的一种有前景的方法。
