Piérard-Franchimont C, Piérard G E
Service de Dermatopathologie, CHU de Liège, Belgique.
Rev Med Liege. 2011 Jan;66(1):34-40.
Malignant melanoma developed after 60 years of age is not a rare neoplasm. It is mainly but not exclusively represented by the lentigo maligna (LM) and the invasive melanoma developed on LM (LMM). Men are more often affected, and chronic sun exposure is the main cause. The diagnosis relies on the clinical, dermoscopic and dermatopathologic examinations. Surgical excision is recommended but alternative treatments are possible in case of contra-indication.
60岁以后发生的恶性黑色素瘤并非罕见肿瘤。它主要但不限于以恶性雀斑样痣（LM）以及发生于LM的侵袭性黑色素瘤（LMM）为代表。男性更常受累，长期阳光照射是主要病因。诊断依靠临床、皮肤镜及皮肤病理学检查。建议手术切除，但在有禁忌证的情况下可采用其他治疗方法。
