Rodrigo F G, Correia M P
Clínica Dermatológica Universitária, Hospital de Santa Maria, Lisboa.
Acta Med Port. 1992 Oct;5(9):485-91.
Malignant Melanoma is a tumor of high malignancy which incidence has been shown to increase dramatically during last decades. The genesis of the tumor is uncertain, however the cutaneous fair complexion, the number and type of pigmented nevei and acute intermittent sun exposure with sunburn may play a significant role in its development. Histopathology of suspicious lesions is obligatory as diagnostic proof and to measure the tumor thickness and the skin invasion level. Distinct therapeutic attitudes are reviewed. Correct surgical excision is essential in localized primary lesions. The two main factors regarding surveillance and survival of patients afflicted with Malignant Melanoma are precocious diagnosis of early lesions and quick surgical intervention. On a prophylactic ground, for the early detection of Malignant Melanoma, one should point out the need for a complete and careful skin observation of every individual in current medical examinations.
恶性黑色素瘤是一种高恶性肿瘤,在过去几十年中其发病率已显示出急剧上升。肿瘤的起源尚不确定,然而皮肤白皙的肤色、色素痣的数量和类型以及伴有晒伤的急性间歇性阳光照射可能在其发展中起重要作用。可疑病变的组织病理学检查作为诊断依据以及测量肿瘤厚度和皮肤浸润程度是必不可少的。本文综述了不同的治疗方法。对于局限性原发性病变,正确的手术切除至关重要。影响恶性黑色素瘤患者监测和生存的两个主要因素是早期病变的早熟诊断和快速手术干预。在预防方面,为了早期发现恶性黑色素瘤,应该指出在当前医学检查中对每个人进行全面仔细的皮肤观察的必要性。