Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
Pathol Res Pract. 2011 Apr 15;207(4):253-5. doi: 10.1016/j.prp.2010.10.002. Epub 2011 Mar 3.
Malignant mixed mullerian tumor (MMMT) is a rare entity. The commonest site of this tumor in the female genital tract is the uterus followed by cervix. Primary MMMT of vagina is extremely rare. We are reporting this rare entity, with a brief review of the literature, in a 48-year-old perimenopausal female who presented with a history of passage of urine per vagina. On pelvic examination, a polypoidal mass arising from the anterior wall of the vagina was identified. Histopathological examination revealed the biphasic nature of the tumor. Immunohistochemistry confirmed the diagnosis of MMMT of vagina. To conclude, although rare, clinicians, oncologists, and pathologists should identify this malignant tumor for appropriate treatment and management.
恶性混合性苗勒管肿瘤（MMMT）是一种罕见的实体瘤。这种肿瘤在女性生殖道中最常见的部位是子宫，其次是宫颈。阴道原发性 MMMT 极为罕见。我们报告了这一罕见的实体瘤，并对文献进行了简要回顾，该患者为 48 岁围绝经期女性，表现为阴道尿失禁。盆腔检查发现阴道前壁有息肉状肿块。组织病理学检查显示肿瘤具有双相性。免疫组织化学证实了阴道 MMMT 的诊断。总之，尽管罕见，但临床医生、肿瘤学家和病理学家应该识别这种恶性肿瘤，以便进行适当的治疗和管理。
