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原发性阴道恶性黑色素瘤——一例病例报告并文献复习

Primary malignant melanoma of vagina--a case report with review of literature.

作者信息

Ghosh A, Pradhan S, Swami R, Kc S R, Talwar O

机构信息

Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2007 Oct-Dec;46(168):203-5.

Abstract

Primary vaginal malignant melanoma is a very rare tumor with less than 300 cases reported to date. We describe a case of primary vaginal melanoma and review the literature. A 60 years postmenopausal female patient presented with painless mass coming out of the vagina with occasional bleeding for last 2-3 weeks. On vaginal examination there was a firm polypoidal growth of size 7 cm attached to the right lateral wall of vagina and coming out of the introitus. Histopathology of the mass showed features of malignant melanoma. Wide local excision was done and adjuvant therapy was given. However patient came back after three months with widespread metastasis and expired 6 months after the initial diagnosis. Vaginal melanoma is a very aggressive tumor and the overall prognosis is very poor despite the treatment modality.

摘要

原发性阴道恶性黑色素瘤是一种非常罕见的肿瘤,迄今为止报道的病例不足300例。我们描述了一例原发性阴道黑色素瘤病例并对文献进行综述。一名60岁绝经后女性患者,在过去2至3周内出现阴道无痛性肿物并伴有偶尔出血。阴道检查发现一个7厘米大小、质地硬的息肉样肿物附着于阴道右侧壁并突出于阴道口。肿物的组织病理学检查显示为恶性黑色素瘤特征。进行了广泛局部切除并给予辅助治疗。然而,患者在三个月后出现广泛转移,在初次诊断后6个月死亡。阴道黑色素瘤是一种极具侵袭性的肿瘤,无论采用何种治疗方式,总体预后都非常差。

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