Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi'an, China.
Maturitas. 2011 Apr;68(4):342-5. doi: 10.1016/j.maturitas.2011.01.018. Epub 2011 Mar 3.
The rising number of obese individuals on a global scale has led the scientific community to determine the causes for this disease. Besides over-consumption of high-caloric foods and/or endocrine dysfunction, food addiction has been found to be a major culprit for weight gain. Food addiction results from craving certain food or food-substances so as to obtain a state of heightened pleasure, energy or excitement. Major intervention is needed in curbing these cravings and suppressing the appetite to promote weight loss. Functional magnetic resonance imaging (fMRI) has been applied to study why obese individuals overeat. Introduction of this technology will serve as a means in paving the way for new weight loss drugs.
在全球范围内，肥胖人群的数量不断增加，这促使科学界确定了导致这种疾病的原因。除了过度摄入高热量食物和/或内分泌功能紊乱外，人们还发现食物成瘾是导致体重增加的一个主要原因。食物成瘾是指对某些食物或食物物质产生强烈的渴望，以获得更高的愉悦感、能量或兴奋感。为了控制这些渴望和抑制食欲以促进减肥，需要进行主要干预。功能性磁共振成像（fMRI）已被应用于研究肥胖者为何暴饮暴食。这项技术的引入将为新型减肥药的研发铺平道路。
