首例先前免疫功能正常的儿童水痘感染转泰勒诺卡氏菌病例。

The first case of Nocardia transvalensis infection in varicella in a previously immunocompetent child.

机构信息

Infectious Disease Unit, Paediatric Department, Bambino Gesù Hospital, Piazza S. Onofrio, 00165 Rome, Italy.

出版信息

Vaccine. 2011 Apr 12;29(17):3103-5. doi: 10.1016/j.vaccine.2011.02.060. Epub 2011 Mar 3.

DOI:10.1016/j.vaccine.2011.02.060

Abstract

A child referred to Infectious Disease Unit for varicella complicated by pneumonia with pleural effusion. Due to not improvement, laboratory search was extended to uncommon pathogens, revealing Nocardia transvalensis infection. It is likely that varicella induced immunodepression, facilitating opportunistic infection in an otherwise healthy and immunocompetent child. To our knowledge, our report is the first case of Nocardia infection in varicella.

摘要

一名儿童因水痘并发肺炎合并胸腔积液而被转介至传染病科。由于病情未见改善，实验室检查扩大到罕见病原体，发现感染了宛氏诺卡菌。水痘可能导致免疫抑制，使原本健康和免疫功能正常的儿童发生机会性感染。据我们所知，我们的报告是首例水痘并发诺卡菌感染。