Sleep and Chronophysiology Laboratory, Department of Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48109-2700, USA.
Behav Res Ther. 2011 Apr;49(4):227-33. doi: 10.1016/j.brat.2011.02.003. Epub 2011 Feb 15.
In a randomized controlled trial, we evaluated the efficacy of cognitive-behavioral treatment for insomnia to improve sleep and daytime symptoms, and to reduce relapse in recovering alcohol dependent (AD) participants. Seventeen abstinent AD patients with insomnia (6 women, mean age 46.2 ± 10.1 years) were randomized to 8 sessions of cognitive-behavioral treatment for insomnia for AD (CBTI-AD, n=9) or to a behavioral placebo treatment (BPT, n=8). Subjective measures of sleep, daytime consequences of insomnia and AD, alcohol use, and treatment fidelity were collected at baseline and post-treatment. Diary-rated sleep efficiency and wake after sleep onset, and daytime ratings of General Fatigue on the Multidimensional Fatigue Inventory improved more in the CBTI-AD compared to the BPT group. In addition, more subjects were classified as treatment responders following CBTI-AD. No group differences were found in the number of participants who relapsed to any drinking or who relapsed to heavy drinking. The findings suggest that cognitive-behavioral insomnia therapy benefits subjective sleep and daytime symptoms in recovering AD participants with insomnia more than placebo. The benefits of treating insomnia on drinking outcomes are less apparent.
在一项随机对照试验中,我们评估了认知行为疗法治疗失眠以改善睡眠和日间症状,并减少正在康复的酒精依赖(AD)患者复发的效果。17 名戒酒的 AD 失眠患者(6 名女性,平均年龄 46.2 ± 10.1 岁)被随机分配到 8 节认知行为疗法治疗 AD 的失眠症(CBTI-AD,n=9)或行为安慰剂治疗(BPT,n=8)。在基线和治疗后收集了睡眠、失眠和 AD 的日间后果、酒精使用和治疗一致性的主观测量值。与 BPT 组相比,CBTI-AD 组的日记评定睡眠效率和入睡后醒来时间以及多维疲劳量表的一般疲劳日间评分有更大的改善。此外,更多的受试者在接受 CBTI-AD 后被归类为治疗反应者。在任何饮酒或重度饮酒复发的参与者数量方面,两组之间没有差异。研究结果表明,认知行为疗法治疗失眠症对正在康复的 AD 失眠患者的主观睡眠和日间症状的益处大于安慰剂。治疗失眠症对饮酒结果的益处不太明显。