Schenken R S
Department of Obstetrics and Gynecology, University of Texas Health Sciences Center, San Antonio 78284.
Am J Obstet Gynecol. 1990 Feb;162(2):579-81. doi: 10.1016/0002-9378(90)90435-a.
A limited number of small studies have assessed the efficacy of gonadotropin-releasing hormone agonists in the treatment of ovarian endometriomas. Most of these trials have not used quantitative measurements to evaluate the effects of therapy on disease resolution. The results available thus far suggest that nafarelin, buserelin, and histrelin offer modest degrees of efficacy, similar to that of danazol, in the management of patients with ovarian endometriotic cysts. Gonadotropin-releasing hormone agonists appear to be most efficacious when endometriomas are less than 1 cm in size.
少数小型研究评估了促性腺激素释放激素激动剂治疗卵巢子宫内膜异位囊肿的疗效。这些试验大多未采用定量测量来评估治疗对疾病消退的影响。目前可得的结果表明，那法瑞林、布舍瑞林和组氨瑞林在治疗卵巢子宫内膜异位囊肿患者方面的疗效与达那唑相似，程度适中。当子宫内膜异位囊肿小于1厘米时，促性腺激素释放激素激动剂似乎最为有效。
