Branchereau A, Rudondy P, Gournier J P, Espinoza H
Service de Chirurgie Vasculaire, Groupe Hospitalier Timone, Marseille, France.
Ann Vasc Surg. 1990 Mar;4(2):138-42. doi: 10.1007/BF02001368.
Between June 1987 and January 1989, a total of 123 albumin-coated, knitted Dacron aortic prosthetic grafts were used in 120 patients. The aim of this study was to determine the degree of graft impermeability to blood as well as short- and medium-term patency of the graft material. Patients were grouped as follows: group I (64 patients), operation for chronic aortoiliac obliteration; group II (45 patients), operation for abdominal aortic aneurysm; group III (14 patients), operation on the thoracic aorta. Ninety-one bifurcated and 32 albumin-coated grafts were inserted. Abnormal bleeding was seen in five cases but did not lead to any adverse clinical consequences and stopped spontaneously. In group I there were two instances of early thromboses thought to be due to hemodynamic compromise, which were successfully treated surgically. In group III, two patients had early thrombosis due to coagulation disorders. These were treated by thrombectomy and medical therapy. One hundred and fourteen patients (95%) were followed for a mean of 8.2 months (range 1-18 months). Three late complications related to the prosthesis were observed: one patient had a false aneurysm occurring at month 14 and was corrected surgically. Two other patients experienced thrombosis of their graft treated by extraanatomical bypasses. Primary patency at the end of the follow-up period was 93% while secondary patency was 98%. There were no early or late infectious complications. We conclude that albumin-coated Dacron prosthesis is a reliable material for aortic replacement. Intraoperative loss of blood is reduced and short- and medium-term patency is comparable to those of uncoated aortic prosthetic material.
1987年6月至1989年1月期间，120例患者共使用了123个白蛋白涂层针织涤纶主动脉人工血管。本研究的目的是确定人工血管对血液的不渗透性程度以及该人工血管材料的短期和中期通畅率。患者分为以下几组：第一组（64例患者），行慢性主-髂动脉闭塞手术；第二组（45例患者），行腹主动脉瘤手术；第三组（14例患者），行胸主动脉手术。植入了91个分叉型和32个白蛋白涂层人工血管。5例出现异常出血，但未导致任何不良临床后果，出血自行停止。第一组有2例早期血栓形成，认为是由于血流动力学障碍所致，经手术成功治疗。第三组有2例患者因凝血障碍出现早期血栓形成，经血栓切除术和药物治疗。114例患者（95%）接受了平均8.2个月（范围1 - 18个月）的随访。观察到3例与人工血管相关的晚期并发症：1例患者在第14个月出现假性动脉瘤，经手术矫正。另外2例患者人工血管发生血栓形成，经解剖外旁路手术治疗。随访期末的一期通畅率为93%，二期通畅率为98%。未出现早期或晚期感染并发症。我们得出结论，白蛋白涂层涤纶人工血管是一种可靠的主动脉置换材料。术中失血减少，短期和中期通畅率与未涂层主动脉人工血管材料相当。
