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产后女性的抑郁风险和自杀症状的季节性影响。

Seasonal effects on depression risk and suicidal symptoms in postpartum women.

机构信息

Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O’Hara Street, Pittsburgh, PA 15213, USA.

出版信息

Depress Anxiety. 2011 May;28(5):400-5. doi: 10.1002/da.20807. Epub 2011 Mar 4.

Abstract

BACKGROUND

Postpartum depression (PPD) is the most common complication of childbirth. Suicide is a leading cause of maternal death in the first postpartum year. Depressed mothers often have suicidal ideation (SI). Depression and suicidality may vary across the seasons. Previous studies of seasonality and PPD were relatively small or encumbered by study design constraints. We examined the possible relationship between seasonality, depression, and SI in 9,339 new mothers.

METHODS

From 2006 to 2010, the investigators screened women within 4-6 weeks postpartum with the Edinburgh Postnatal Depression Scale (EPDS). We used spectral analysis to explore seasonal variation in risk for depression and suicidality.

RESULTS

The study team screened 9,339 new mothers, of whom 1,316 (14%) women had positive depression scores (EPDS≥10) which suggest PPD risk; 294 (3%) women had SI (item 10≥1). A positive EPDS was associated significantly with SI. PPD risk varied significantly across 12-months-risk was highest in December. We detected no seasonal variation in SI.

CONCLUSIONS

Effects of seasonal light variation may contribute to increased risk for depressive symptoms. Suicidality could be related to maternal depression but not seasonal variation.

摘要

背景

产后抑郁症(PPD)是分娩后最常见的并发症。自杀是产后第一年产妇死亡的主要原因。抑郁的母亲常有自杀意念(SI)。抑郁和自杀倾向可能会随季节变化而变化。先前关于季节性和 PPD 的研究相对较小,或者受到研究设计限制的困扰。我们研究了 9339 名新妈妈中季节性、抑郁和 SI 之间的可能关系。

方法

2006 年至 2010 年,研究人员在产后 4-6 周内用爱丁堡产后抑郁量表(EPDS)对女性进行筛查。我们使用频谱分析来探索抑郁和自杀倾向的季节性变化。

结果

研究小组共筛查了 9339 名新妈妈,其中 1316 名(14%)女性的抑郁评分(EPDS≥10)呈阳性,提示有 PPD 风险;294 名(3%)女性有 SI(项目 10≥1)。阳性 EPDS 与 SI 显著相关。PPD 风险在 12 个月内变化显著,风险在 12 月最高。我们没有检测到 SI 的季节性变化。

结论

季节性光照变化的影响可能导致抑郁症状风险增加。自杀倾向可能与母亲的抑郁有关,但与季节性变化无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9a0/3107602/a45195f5b85a/nihms294410f1.jpg

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