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肺动脉分支狭窄球囊血管成形术的早期结果及随访

Early results and follow-up of balloon angioplasty for branch pulmonary artery stenoses.

作者信息

Rothman A, Perry S B, Keane J F, Lock J E

机构信息

Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

出版信息

J Am Coll Cardiol. 1990 Apr;15(5):1109-17. doi: 10.1016/0735-1097(90)90250-s.

Abstract

Two hundred eighteen balloon angioplasty procedures were performed in 135 patients with branch pulmonary artery stenoses from June 1984 to February 1989. Arteries were dilated in patients with tetralogy of Fallot (n = 49), tetralogy of Fallot/pulmonary atresia (n = 64), isolated peripheral pulmonary artery stenoses (n = 58) and "other" lesions (the majority had truncus arteriosus or single ventricle and surgically induced pulmonary artery stenoses (n = 47). Mean age at dilation was 6.6 +/- 6.3 years (range 1 month to 38.5 years). The mean diameter of the lesion increased from 3.8 +/- 1.7 to 5.5 +/- 2.1 mm with dilation (p = 0.001). The overall success rate was 58% (127 of 218 dilations), assessed by the following criteria: an increase greater than or equal to 50% of predilation diameter, an increase greater than 20% in flow to the affected lung or a decrease greater than 20% in systolic right ventricular to aortic pressure ratio. Success did not correlate with patient age. Mean balloon to artery ratio was higher in successful (4.2) than in failed (3.0) angioplasty procedures (p = 0.0001). There were four early deaths: two of the patients had pulmonary artery rupture with angioplasty performed less than 1 month after pulmonary artery surgery. An aneurysm occurred in 11 arteries and transient pulmonary edema in four patients. At angiography performed a mean of 10 months (range 1 to 54) after dilation, the mean diameter of 57 arteries was unchanged (5.5 versus 5.4 mm). However, 5 of 32 initially successfully dilated vessels had returned to predilation size as a result of restenosis.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1984年6月至1989年2月期间,对135例分支肺动脉狭窄患者实施了218例球囊血管成形术。法洛四联症患者(n = 49)、法洛四联症/肺动脉闭锁患者(n = 64)、孤立性外周肺动脉狭窄患者(n = 58)以及“其他”病变患者(大多数为共同动脉干或单心室且有外科手术导致的肺动脉狭窄,n = 47)的动脉均进行了扩张。扩张时的平均年龄为6.6±6.3岁(范围1个月至38.5岁)。病变的平均直径经扩张后从3.8±1.7毫米增加至5.5±2.1毫米(p = 0.001)。根据以下标准评估,总体成功率为58%(218次扩张中的127次):扩张后直径增加大于或等于扩张前直径的50%、流向患肺的血流量增加大于20%或收缩期右心室与主动脉压力比值降低大于20%。成功率与患者年龄无关。成功的血管成形术(4.2)中球囊与动脉的平均比值高于失败的血管成形术(3.0)(p = 0.0001)。有4例早期死亡:2例患者在肺动脉手术后不到1个月进行血管成形术时发生肺动脉破裂。11条动脉出现动脉瘤,4例患者出现短暂性肺水肿。在扩张后平均10个月(范围1至54个月)进行的血管造影检查中,57条动脉的平均直径未变(5.5毫米对5.4毫米)。然而,32条最初成功扩张的血管中有5条因再狭窄而恢复到扩张前大小。(摘要截选至250词)

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