Gichner T, Badaev S A, Pospísil F, Velemínský J
Institute of Experimental Botany, Prague, Czechoslovakia.
Mutat Res. 1990 Mar;229(1):37-41. doi: 10.1016/0027-5107(90)90006-p.
Nitrosation of the carbamate insecticide propoxur at pH 3 and 37 degrees C was determined colorimetrically and found to be time- and sodium nitrite concentration-dependent. Nitrosated propoxur was mutagenic when exposed to the seeds of the higher plant Arabidopsis thaliana but the formation of nitrosopropoxur, the presumed mutagen, was inhibited by humic acids, para-aminobenzoic acid and ascorbic acid. These agents also reduced the mutagenicity of preformed nitrosopropoxur.
