Department of Clinical Psychology, VU University Amsterdam, Van der Boechorststraat 1, Amsterdam, The Netherlands.
Clin Psychol Rev. 2011 Apr;31(3):353-60. doi: 10.1016/j.cpr.2011.01.002. Epub 2011 Jan 16.
Research on psychological treatment of depression in inpatients is not conclusive, with some studies finding clear positive effects and other studies finding no significant benefit compared to usual care or structured pharmacotherapy. The results of a meta-analysis investigating how effective psychological treatment is for depressed inpatients are presented. A systematic search in bibliographical databases resulted in 12 studies with a total of 570 respondents. This set of studies had sufficient statistical power to detect small effect sizes. Psychological treatments had a small (g=0.29), but statistically significant additional effect on depression compared to usual care and structured pharmacological treatments only. This corresponded with a numbers-needed-to-be-treated of 6.17. Heterogeneity was zero in most analyses, and not significant in all analyses. There was no indication for significant publication bias. Effects were not associated with characteristics of the population, the interventions and the design of the studies. Although the number of studies was small, and the quality of many studies was not optimal, it seems safe to conclude that psychological treatments have a small but robust effect on depression in depressed inpatients. More high-quality research is needed to verify these results.
住院患者抑郁的心理治疗研究尚无定论，一些研究发现其具有明显的积极效果，而其他研究则发现与常规护理或结构化药物治疗相比并无显著益处。本文呈现了一项荟萃分析，旨在调查心理治疗对住院抑郁患者的有效性。通过对文献数据库进行系统检索，共纳入了 12 项研究，总计 570 名受访者。这组研究具有足够的统计效能来检测小效应量。与常规护理和结构化药物治疗相比，心理治疗对抑郁的额外影响较小（g=0.29），但具有统计学意义。这相当于需要治疗的人数为 6.17。大多数分析中异质性为零，所有分析中均无显著性。没有迹象表明存在显著的发表偏倚。治疗效果与人群特征、干预措施和研究设计无关。尽管研究数量较少，且许多研究的质量并不理想，但似乎可以安全地得出结论，即心理治疗对住院抑郁患者的抑郁具有较小但稳健的影响。需要更多高质量的研究来验证这些结果。
