Minette A
Rev Inst Hyg Mines (Hasselt). 1977;32(2):51-75.
In a first chapter the author reviews the mechanisms of action of corticoids in respiratory diseases. Moreover the causes and the prevalence of unwanted side-effects are discussed. The advantages of synthetic glucocorticoids with short half-life time in pneumology are stressed. In the following chapters, the rationale of long-term corticoid treatments of asthma, in non allergic obstructive chronic lung diseases, in sarcoidosis and in the thoracic localisations of some collagen diseases is presented in detail. Regarding the treatment of asthma the author discusses the advantages of the alternate-day therapy, the use of corticoids in aerosols and the ratioale of ACTH. The usefulness of alternate-day therapy in sarcoidosis is also advocated.
在第一章中，作者回顾了皮质激素在呼吸系统疾病中的作用机制。此外，还讨论了不良反应的原因和发生率。强调了半衰期短的合成糖皮质激素在肺病学中的优势。在接下来的章节中，详细介绍了在哮喘、非过敏性阻塞性慢性肺病、结节病以及某些胶原疾病的胸部病变中进行长期皮质激素治疗的基本原理。关于哮喘的治疗，作者讨论了隔日疗法的优势、气雾剂中皮质激素的使用以及促肾上腺皮质激素的基本原理。还提倡隔日疗法在结节病中的应用。
