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社区药房的药物基因组学:现在就行动。

Pharmacogenomics in a community pharmacy: ACT now.

机构信息

Kerr Health Care Center, Kerr Drug, Chapel Hill, NC, USA.

出版信息

J Am Pharm Assoc (2003). 2011 Mar-Apr;51(2):189-93. doi: 10.1331/JAPhA.2011.10178.

DOI:10.1331/JAPhA.2011.10178
PMID:21382809
Abstract

OBJECTIVE

To highlight the opportunity for community pharmacists to provide pharmacogenomic testing and counseling.

DATA SOURCES

Peer-reviewed pharmacy literature.

SUMMARY

Pharmacists practicing in community pharmacy are accustomed to optimizing drug therapy through various medication therapy management programs. They use patient-specific information obtained from the patient and their prescribers to cater patient-specific drug regimens. Pharmacogenomics is rapidly evolving, and this field can help optimize medication therapy using an individual's genetic code to identify opportunities for increased or decreased adverse effects or changes in efficacy. Pharmacogenomic testing technology has made conducting pharmacogenomic testing in community pharmacies possible. Pharmacists must arm themselves with the knowledge and skills specific to pharmacogenomics in order to fully integrate this expanding area into patient care and turn this into a great opportunity.

CONCLUSION

Advances in knowledge and technology regarding pharmacogenomics coupled with the overwhelming access and use of a community pharmacist by patients provides a tremendous opportunity for community pharmacists to lay claim to the field of pharmacogenomics. Pharmacists are able and needed to provide testing, evaluate results, and offer patient and prescriber education for pharmacogenomics. Pharmacists must take steps to assess the entire clinical picture and use pharmacogenomics where appropriate to optimize drug therapy.

摘要

目的

强调社区药剂师提供药物基因组学检测和咨询的机会。

资料来源

同行评议的药学文献。

概述

在社区药房执业的药剂师习惯于通过各种药物治疗管理计划来优化药物治疗。他们使用从患者及其处方医生那里获得的患者特定信息来制定针对患者的药物治疗方案。药物基因组学正在迅速发展,该领域可以利用个体的遗传密码来优化药物治疗,以确定增加或减少不良反应或疗效变化的机会。药物基因组学检测技术使在社区药房进行药物基因组学检测成为可能。药剂师必须掌握特定于药物基因组学的知识和技能,以便将这一不断扩展的领域全面融入患者护理,并将其转化为巨大的机遇。

结论

药物基因组学知识和技术的进步,加上患者对社区药剂师的压倒性接触和使用,为社区药剂师提供了一个巨大的机会,可以宣称自己在药物基因组学领域的地位。药剂师能够且需要提供检测、评估结果,并为药物基因组学提供患者和处方医生的教育。药剂师必须采取措施评估整个临床情况,并在适当的情况下使用药物基因组学来优化药物治疗。

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