儿童中出现的甲胎蛋白阴性的肝脏囊性病变应让人想到肝母细胞瘤。

AFP negative cystic liver lesion in a child should let one think of hepatoblastoma.

作者信息

Goedeke Jan, Haeberle Beate, Schmid Irene, von Schweinitz Dietrich

机构信息

Department of Pediatric Surgery, Dr von Haunersches Children's Hospital, Ludwigs-Maximilians-University of Munich, Munich.

出版信息

J Pediatr Hematol Oncol. 2011 Aug;33(6):e245-7. doi: 10.1097/MPH.0b013e3181f466ec.

DOI:10.1097/MPH.0b013e3181f466ec

PMID:21383638

Abstract

AFP is still the most important serologic marker for the hepatoblastoma as the most common liver tumor in children. An AFP negative hepatoblastoma is rare. We present the first documented case of an infant with an AFP negative and cystic liver lesion later diagnosed as a fetal hepatoblastoma.

摘要

甲胎蛋白（AFP）仍是肝母细胞瘤最重要的血清学标志物，肝母细胞瘤是儿童最常见的肝脏肿瘤。AFP阴性的肝母细胞瘤很罕见。我们报告首例有记录的婴儿病例，该婴儿有AFP阴性的肝脏囊性病变，后来被诊断为胎儿型肝母细胞瘤。