[急性乙型肝炎中的系统e]
[System e in acute hepatitis B].
作者信息
Esteban R, Pedreira J D, Guardia J, Martinez-Vazquez J M, Gallart T, Bacardi R
出版信息
Sem Hop. 1978;54(21-24):717-8.
HBeAg and Ab are investigated by simple radial immunodiffusion in dextrane following Magnius. 14 patients (28%) were HBeAg positive and 2 patients HBeAb positive (4%). HBsAg subtyping was ad in 6 cases and ay in further 5. No relation was found between both determinants and HBeAg. Six of the 10 patients with HBeAg in their sera developed chronic liver disease o fulminant hepatitis, while only 3 of the 21 HBeAg negative controls did so (p less than 0.05). HBeAg is a marker of the evolution of virus B hepatitis.
采用马格尼乌斯（Magnius）方法，在右旋糖酐中通过简单的放射免疫扩散法检测HBeAg和抗体。14例患者（28%）HBeAg呈阳性，2例患者HBeAb呈阳性（4%）。6例患者的HBsAg亚型为ad，另外5例为ay。未发现这两种决定簇与HBeAg之间存在关联。血清中HBeAg阳性的10例患者中有6例发展为慢性肝病或暴发性肝炎，而21例HBeAg阴性对照中只有3例出现这种情况（p<0.05）。HBeAg是乙型肝炎病毒演变的一个标志物。
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