Reichlin B, Stalder G A, Gudat F, Bianchi L, Froesner G G
Schweiz Med Wochenschr. 1982 Apr 12;112(15):523-4.
The correlation of HBeAg, anti-HBe, Dane particles and results of light microscopy of liver biopsies have been studied in 109 patients with chronic HBV infection and in 21 HBsAg carriers. The following conclusions may be drawn: 1. There is a good correlation between the presence of HBeAg and Dane particles. 2. Patients with both of these markers often have chronic active or lobular hepatitis. 3. The presence of anti-HBe points in 80% of these cases to a carriership or chronic persistent hepatitis. 4. 60% of patients without an HBe-marker and 20% of patients with anti-HBe exhibit presence of Dane particles.
对109例慢性乙肝病毒感染患者和21例乙肝表面抗原携带者的乙肝e抗原、乙肝e抗体、丹氏颗粒与肝活检光镜检查结果之间的相关性进行了研究。可得出以下结论:1. 乙肝e抗原和丹氏颗粒的存在之间存在良好的相关性。2. 同时具有这两种标志物的患者常患有慢性活动性或小叶性肝炎。3. 在这些病例中,80%的乙肝e抗体阳性表明为携带者状态或慢性持续性肝炎。4. 60%无乙肝e标志物的患者和20%有乙肝e抗体的患者存在丹氏颗粒。