Hautecouverture M, Luton J P
Sem Hop. 1978;54(21-24):764-70.
Glucocorticoids increase the stocks of carbohydrate and the supra-hepatic flow of glucose. Their excess produces a centripetal redistribtution of adipose stocks and potentialises adipocyte lipolysis. Although their role of glucose and lipid metabolism is evident, the mechanisms and sites of action of glucocorticoids are multiple and not entirely clear. The actions of glucocorticoids become clear in cases of insulin deficiency, especially when the deficiency is marked, which is of great interest in current medical practice.
糖皮质激素会增加碳水化合物储备以及肝脏上方的葡萄糖流量。其过量会导致脂肪储备向心性重新分布,并增强脂肪细胞的脂解作用。尽管糖皮质激素在葡萄糖和脂质代谢中的作用很明显,但其作用机制和作用位点是多方面的,且并不完全清楚。在胰岛素缺乏的情况下,尤其是严重缺乏时,糖皮质激素的作用就会变得明显,这在当前医学实践中具有重要意义。