Morgan Sara
Cardiff and Vale University Health Board.
Emerg Nurse. 2011 Feb;18(9):22-5. doi: 10.7748/en2011.02.18.9.22.c8337.
Non-steroidal anti-inflammatory drugs and opioids have been the mainstay of pain relief in patients with renal colic, but both have side effects. Research on the efficacy of intravenous (IV) paracetamol shows that it is comparable to morphine, diclofenac and ketoralac. This article discusses the role of IV paracetamol for patients with this condition. It examines the effectiveness, mechanism of action and pharmacokinetics of IV paracetamol, and suggests that non-clinical prescribers can use the method to relieve patients' pain quickly.
非甾体抗炎药和阿片类药物一直是肾绞痛患者缓解疼痛的主要药物,但两者都有副作用。对静脉注射扑热息痛疗效的研究表明,其效果与吗啡、双氯芬酸和酮咯酸相当。本文讨论了静脉注射扑热息痛在这类患者中的作用。它研究了静脉注射扑热息痛的有效性、作用机制和药代动力学,并表明非临床开处方者可以使用该方法快速缓解患者疼痛。