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毒红菇急性中毒——临床病程

Acute intoxication with Tricholoma equestre--clinical course.

作者信息

Sein Anand Jacek, Chwaluk Paweł

机构信息

Pomerania Center of Toxicology, Gdańsk, Poland.

出版信息

Przegl Lek. 2010;67(8):617-8.

PMID:21384788
Abstract

UNLABELLED

We observed all patients admitted to the poison centers for children and adults in Gdańsk and Biała Podlaska, between the years 2001 and 2010, who were intoxicated with Tricholoma equestre. The main clinical symptoms, included muscle weakness, nausea without vomiting, diaphoresis without fever, and in the most serious cases acute respiratory failure. In biochemical results there were seen marked increase in CK, AST and ALT levels. The mortality rate was 20%. It seems that the severity of intoxication are correlated with the amount of ingested mushroom.

CONCLUSIONS

Physicians should be aware of the possibility of acute intoxications after repeated consumption of large quantities of Tricholoma equestre. The clinical picture of poisonings with this wild mushroom might be different in children and adults and depends on ingested amount of these mushrooms. The most serious adverse effect include acute respiratory failure and myocarditis with cardiac arrhythmia and cardiovascular collapse. Intoxication of Tricholoma equestre may be connected with the high mortality rate about 20%.

摘要

未标注

我们观察了2001年至2010年间在格但斯克和比亚瓦-波德拉斯卡的儿童和成人中毒控制中心收治的所有因误食毒蝇伞而中毒的患者。主要临床症状包括肌肉无力、无呕吐的恶心、无发热的多汗,在最严重的情况下会出现急性呼吸衰竭。生化检查结果显示肌酸激酶(CK)、天冬氨酸转氨酶(AST)和丙氨酸转氨酶(ALT)水平显著升高。死亡率为20%。中毒的严重程度似乎与摄入蘑菇的量相关。

结论

医生应意识到反复大量食用毒蝇伞后可能发生急性中毒。这种野生蘑菇中毒的临床表现可能因儿童和成人而异,且取决于摄入蘑菇的量。最严重的不良反应包括急性呼吸衰竭、伴有心律失常和心血管虚脱的心肌炎。毒蝇伞中毒可能与约20%的高死亡率相关。

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