微波辅助桥头烯烃的合成。
Microwave assisted synthesis of bridgehead alkenes.
机构信息
Department of Chemistry, University of California, Irvine, 1102 Natural Sciences 2, Irvine, California 92697-2025, United States.
出版信息
Org Lett. 2011 Apr 1;13(7):1781-3. doi: 10.1021/ol200244p. Epub 2011 Mar 8.
Abstract
A new, concise method to synthesize triene precursors for the type 2 intramolecular Diels-Alder reaction has been developed. Microwave irradiation of the trienes provides a convenient method for the synthesis of bridgehead alkenes. Higher yields, shorter reaction times, and lower reaction temperatures provide a general and efficient route to this interesting class of molecules.
摘要
现已开发出一种新的、简洁的方法来合成用于 2 型分子内 Diels-Alder 反应的三烯前体。三烯的微波辐射为桥环烯烃的合成提供了一种便利的方法。更高的产率、更短的反应时间和更低的反应温度为这类有趣的分子提供了一种通用且高效的途径。
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