法医 DNA 分型的过去、现在和未来。

Past, present and future of forensic DNA typing.

机构信息

Centre of Excellence for Genomic Risk Assessment in Multifactorial & Complex Diseases, School of Medicine, University of Rome Tor Vergata, Rome, Italy.

出版信息

Nanomedicine (Lond). 2011 Feb;6(2):257-70. doi: 10.2217/nnm.10.160.

DOI:10.2217/nnm.10.160

PMID:21385128

Abstract

Recent advances in our ability to dissect the human genome and the availability of platforms for genome-wide analysis and whole-genome sequencing are expected to develop new tools for both biomedical and forensic DNA analyses. Nowadays, we can individualize single cells left at the crime scene or analyze ancient human remains. Here, we provide a general view on the past, current and likely future directions of forensic DNA analysis.

摘要

近年来，我们在解析人类基因组方面的能力取得了进展，并且出现了用于全基因组分析和全基因组测序的平台，这有望为法医生物 DNA 分析开发新工具。如今，我们可以对犯罪现场遗留的单个细胞进行个体化分析，或者分析古代人类遗骸。在此，我们提供了关于法医 DNA 分析过去、现在和未来可能方向的概述。