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纳米材料在传染病诊断阵列中的应用。

Application of nanomaterials to arrays for infectious disease diagnosis.

机构信息

Health Protection Agency, Centre for Infections, London, UK.

出版信息

Nanomedicine (Lond). 2011 Feb;6(2):271-80. doi: 10.2217/nnm.10.161.

Abstract

As our understanding of infectious agents increases it has become possible to identify the biological components of individual strains with greater accuracy. This ability is aiding clinical microbiologists to control both existing and emerging infectious disease problems. Microarray technologies are playing an increasingly important role in supplying relevant test data. Control of the nanoscale structures of the materials used in arrays, including the supports, reagents and analytes, is now essential. New techniques for the manufacture of nanostructured supports is now allowing rapid advances in the fields of multianalyte testing and high-volume DNA sequencing.

摘要

随着我们对传染因子的了解不断加深,现在已经有可能更准确地识别出各个菌株的生物成分。这种能力正在帮助临床微生物学家控制现有的和新出现的传染病问题。微阵列技术在提供相关测试数据方面发挥着越来越重要的作用。现在,控制阵列中使用的材料的纳米级结构,包括载体、试剂和分析物,是至关重要的。用于制造纳米结构载体的新技术现在正在使多分析物检测和高通量 DNA 测序领域取得快速进展。

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