Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN 55108, USA.
J Breath Res. 2010 Mar;4(1):017106. doi: 10.1088/1752-7155/4/1/017106. Epub 2010 Feb 18.
Volatile sulfur compounds (VSCs), specifically hydrogen sulfide, methyl mercaptan and dimethyl sulfide, are generally considered to be the primary volatiles responsible for 'morning' malodors in breath. To date, the 'gold standard' for detecting VSC concentrations in breath is the use of gas chromatography coupled with sulfur chemiluminescence detection. Breath gas is often collected in a polypropylene syringe and then aliquots are injected into a gas chromatograph for analysis. The objective of this work was to compare the Twister™ bar in-mouth extraction methodology for measurement of VSCs with the gas syringe breath-sampling collection technique. The Twister bar technology captures malodorous compounds in the mouth as opposed to breath gas. Using these techniques, comparable results were obtained in studies demonstrating the efficacy of a proprietary oral malodor counteraction system.
挥发性硫化合物(VSCs),特别是硫化氢、甲硫醇和二甲硫醚,通常被认为是导致口气中“早晨”异味的主要挥发性物质。迄今为止,检测口气中 VSC 浓度的“金标准”是使用气相色谱法结合硫化学发光检测法。口气通常收集在一个聚丙烯注射器中,然后取等分试样注入气相色谱仪进行分析。这项工作的目的是比较 Twister™ 口内提取法测量 VSCs 与气体注射器呼吸采样收集技术。Twister 棒技术捕捉口中的恶臭化合物,而不是口气中的气体。使用这些技术,在证明一种专利口腔异味对抗系统的功效的研究中,获得了可比的结果。