Fekih Leila, Boussoffara Leila, Chaouachi Soumaya, Fenniche Soraya, Abdelghaffar Hajer, Akrout Ines, Hassene Hela, Belhabib Dalenda, Megdiche Mohamed Lamine
Service de Pneumologie Ibn Nafiss, Hôpital Abderrahmen Mami, Ariana, Tunisie.
Tunis Med. 2011 Mar;89(3):269-73.
Systemic lupus erythematosus (SLE) is an autoimmune disease. The respiratory system is more commonly involved in SLE than in any other collagen vascular disease.
To study the pleuropulmonary manifestations of SLE.
Retrospective study including 10 patients hospitalized between January 2000 and December 2008 for pleuro-pulmonary manifestation revealing or complicating the SLE.
Nine women and only one man aged between 21 and 67 years-old were included in this study. Two patients had already SLE and for the other patients the pleuro-pulmonary manifestations were revealing the SLE. Pleural effusion was the most common manifestation witch represents 50% of the patients. For the other patients we find one case of interstitial pneumonia, one case of pulmonary embolism, on case of pneumonia, on case of pulmonary haemorrhage and on case of pulmonary hypertension. All these patients were treated by corticoids and only one patient takes high doses of corticoids for managing a massive pulmonary haemorrhage. The evolution was favourable for 9 patients, one patient dead because of massive pulmonary haemorrhage complicated with acute respiratory failure.
Pleuro-pulmonary involvement in SLE is common and may be life threatening, in which case prompt and aggressive treatment is mandatory.
系统性红斑狼疮（SLE）是一种自身免疫性疾病。与其他任何胶原血管病相比，呼吸系统在SLE中更常受累。
研究SLE的胸膜肺部表现。
回顾性研究，纳入2000年1月至2008年12月间因胸膜肺部表现而住院的10例患者，这些表现揭示或并发SLE。
本研究纳入9名女性和1名男性，年龄在21至67岁之间。2例患者已有SLE，其他患者的胸膜肺部表现为SLE首发症状。胸腔积液是最常见的表现，占患者的50%。其他患者中，我们发现1例间质性肺炎、1例肺栓塞、1例肺炎、1例肺出血和1例肺动脉高压。所有这些患者均接受皮质类固醇治疗，只有1例患者因大量肺出血而服用大剂量皮质类固醇。9例患者病情好转，1例患者因大量肺出血并发急性呼吸衰竭死亡。
SLE的胸膜肺部受累很常见，且可能危及生命，在这种情况下，必须迅速进行积极治疗。
