Memet Beatrice, Ginzler Ellen M
Division of Rheumatology, State University of New York-Downstate Medical Center, Brooklyn, New York 11203, USA.
Semin Respir Crit Care Med. 2007 Aug;28(4):441-50. doi: 10.1055/s-2007-985665.
Systemic lupus erythematosus (SLE) can affect the lung in multiple ways. All components of the respiratory system, including the pleura, pulmonary parenchyma, airways, vessels, and respiratory muscles can be involved in various degrees at some time in the disease course and contribute to its morbidity and mortality. This article reviews the clinical symptoms, imaging techniques, histopathology, prognosis, and treatment of pulmonary manifestations of SLE and the related disorder mixed connective tissue disease (MCTD), from a historical perspective and with regard to new insights into pathogenesis and therapy.
系统性红斑狼疮（SLE）可通过多种方式累及肺部。在疾病进程中的某些时候，呼吸系统的所有组成部分，包括胸膜、肺实质、气道、血管和呼吸肌，均可不同程度地受累，并导致其发病和死亡。本文从历史角度以及对发病机制和治疗的新见解方面，综述了SLE及相关疾病混合性结缔组织病（MCTD）肺部表现的临床症状、影像学技术、组织病理学、预后及治疗。
